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BOLD CLINICAL ANALYSIS:

ESSENTIAL OIL MOUTHWASH EFFECT ON GUM PROBLEMS AND PLAQUE

A landmark, peer-reviewed analysis of 29 studies involving over 5000 patients has provided the most conclusive evidence to date on the additive benefits of LISTERINE® mouthwash in plaque and gum problems reduction. Its results confirm that a world of better oral health is not only possible, but attainable—and it all starts with your practice.

 Landmark, peer-reviewed analysis adds clinical relevance for your everyday practice 

  1. Results reported by sites healthy and plaque-free—as opposed to whole-mouth plaque/gingivitis reduction data—allow you to easily set targets for your practice

  2. This analysis reviewed data on the additive benefits of LISTERINE® from randomized, observer-blinded, placebo-controlled studies, including both published and unpublished data

  3. Evidence was drawn from a larger-than-usual population of N>5000 subjects; single studies have an average of 163 subjects

 The most robust collection of clinical data of its kind 

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  • 1 landmark analysis: enabled broader, more clinically relevant conclusions

 Analysis compared the results of 2 treatment groups 

 Control group 

  • Mechanical methods (MM) alone

  • 2562 patients

 Experimental group 

  • MM + LISTERINE®

  • 2544 patients

Sitewise analysis evaluated efficacy at multiple sites per tooth across the entire mouth

 Plaque index (PI): 6 sites per tooth 

  • Plaque-free sites were defined as those with small pieces of plaque (1) or no plaque (0), based on the PI score

 Modified gingival index (MGI): 4 sites per tooth 

  • Healthy sites were defined as those with mild (1) to no (0) inflammation, based on the MGI scores

 LISTERINE® users were more likely to have a cleaner, healthier mouth vs. MM alone 

claims 5x and 2x

 LISTERINE® users had more plaque-free sites and more healthy sites — even in the hardest-to-reach areas of the mouth 

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 Reference: 1.  Araujo MWB, Charles CA, Weinstein RB, et al. Meta-analysis of the effect of an essential oil–containing mouthrinse on gingivitis and plaque.  J Am Dent Assoc . 2015;146(8):610-622 and/or post hoc analyses of data.

Publications

How LISTERINE® Works

LISTERINE® vs. Other Rinses

Safety & Tolerability

BIG RESULTS FROM THE BIGGEST LISTERINE® ANALYSIS.

EVER.